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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 50-year-old patient presents to the physician complaining of anxiety, insomnia, a depressed mood, and decreased energy level. Paroxetine therapy is initiated. Which symptom will be the last to respond?

A) Depressed mood
B) Anxiety
C) Decreased energy
D) Insomnia

2. Using a new assay, the following readings for Drug X concentration in a blood sample are obtained: 45 ng/mL, 43 ng/mL, 45 ng/mL, 44 ng/mL, 45 ng/mL, and 45 ng/mL. The true concentration of the drug was reported as 65 ng/mL using the gold-standard assay.
On the basis of these data, the new assay should be characterized in which of the following categories?

A) Both accurate and precise
B) Accurate but not precise
C) Neither accurate nor precise
D) Precise but not accurate

3. A patient with rheumatoid arthritis has been experiencing increased pain over the last 2-3 weeks. The patient's rheumatoid arthritis has previously been controlled with methotrexate and periodic NSAID and steroid use for acute flares. However, currently this regimen is inadequate.
The physician wants to initiate therapy with etanercept.
Which of the following infections should be screened for prior to initiating therapy?

A) Candida
B) Legionella
C) Hepatitis A
D) Tuberculosis

4. In a clinical trial, when would "intention to treat" analysis be most appropriate?

A) Crossover design
B) Small sample size
C) High drop-out rate
D) Phase || trial

5. A 38-year-old man with stage II testicular cancer has received a 5-day course of Cisplatin and etoposide, followed by daily Filgrastim. On day 14, he reports duki aching bone pain. Which of the following is the most likely cause of this complaint?

A) Filgrastim
B) Disease progression
C) Cisplatin
D) Etoposide

Solutions: